Table 1.
Mean ± SEM area (mm2) and percentage (%) of the lesion area of the total area of the given cytoarchitectonic cortical region. Number of animals with a lesion in a given cortical subfield is in parentheses (n). No difference in lesion area was detected between groups.
| TBI-VEH (n =10) |
TBI-DUO (n = 10) |
|||
|---|---|---|---|---|
| Area | mm2 ± SEM | % (n) | mm2 ± SEM | % (n) |
| PRh | 0.35 | 10% (1/10) | 1.02 | 29% (1/10) |
| Ect | 0.95 ± 0.43 | 18% (6/10) | 1.88 ± 1.08 | 14% (9/10) |
| TeA | 1.93 ± 0.27 | 49% (9/10) | 6.99 ± 5.01 | 45% (9/10) |
| Au1 | 3.62 ± 0.48 | 62% (10/10) | 6.62 ± 3.51 | 48% (10/10) |
| AuD | 2.40 ± 0.09 | 92% (10/10) | 9.12 ± 6.88 | 78% (10/10) |
| AuV | 0.71 ± 0.20 | 27% (9/10) | 2.11 ± 1.43 | 24% (8/10) |
| S1 | 1.19 ± 0.02 | 97% (10/10) | 10.19 ± 8.98 | 89% (10/10) |
| S1BF | 5.55 ± 0.63 | 49% (10/10) | 6.79 ± 1.61 | 43% (10/10) |
| S1DZ | 0.12 ± 0.07 | 7% (3/10) | 0.08 ± 0.05 | 4% (2/10) |
| S1FL | 0.10 | 1% (1/10) | 0 | 0% (0/10) |
| S1ULp | 1.17 ± 0.23 | 13% (9/10) | 0.84 ± 0.18 | 8% (8/10) |
| S2 | 0.76 ± 0.20 | 11% (9/10) | 0.79 ± 0.25 | 7% (7/10) |
| PtPD | 0.25 ± 0.09 | 26% (6/10) | 0.32 ± 0.08 | 33% (10/10) |
| PtPR | 0.50 ± 0.056 | 67% (10/10) | 0.64 ± 0.038 | 86% (10/10) |
| V1 | 0.11 ± 0 | 5% (2/10) | 0.66 ± 0.62 | 31% (3/10) |
| V1B | 1.45 ± 0.36 | 28% (8/10) | 1.86 ± 0.41 | 37% (10/10) |
| V1M | 1.21 ± 0.52 | 21% (5/10) | 0.92 ± 0.35 | 16% (6/10) |
| V2L | 4.46 ± 0.40 | 69% (10/10) | 5.21 ± 0.30 | 80% (10/10) |
| V2ML | 0.29 ± 0.17 | 9% (2/10) | 0.19 ± 0.05 | 6% (3/10) |
| V2MM | 0.75 | 18% (1/10) | 0.32 ± 0.09 | 8% (2/10) |
| RSD | 1.02 | 10% (1/10) | 0 | 0% (0/10) |
| Total lesion area | 24.65 ± 3.21 | 5% (10/10) | 24.87 ± 3.24 | 5% (10/10) |
Abbreviations: Au1, primary auditory cortex; AuD, secondary auditory cortex, dorsal area; AuV, secondary auditory cortex, ventral area; Ect, ectorhinal cortex; PRh, perirhinal cortex; PtPD, parietal cortex, posterior area, dorsal part; PtPR, parietal cortex, posterior area, rostral part; RSD, retrosplenial dysgranular cortex; S1, primary somatosensory cortex; S1BF, primary somatosensory cortex, barrel field; S1DZ, primary somatosensory cortex, dysgranular zone; S1FL, primary somatosensory cortex, forelimb region; S1ULp, primary somatosensory cortex, upper lip region; S2, secondary somatosensory cortex; TBI, traumatic brain injury; TeA, temporal associatin cortex; V1, primary visual cortex; V1B, primary visual cortex, binocular area; V1M, primary visual cortex, monocular area; V2L, secondary visual cortex, lateral area; V2ML, secondary visual cortex, mediolateral area; V2MM, secondary visual cortex, mediomedial area.