Figure 7.

Glucose metabolism in muscle, palmitate oxidation in heart and triglyceride content in muscle and heart. (A) Glucose oxidation was measured ex vivo by release of CO₂. (B) Glucose incorporation into glycogen of diaphragm. (C) Palmitate oxidation measured ex vivo by the release of CO₂ in myocardium. (D) TAG concentrations related to weight of tissue (myocardium and muscle gastrocnemius). Control group (n = 7) and empagliflozin group (n = 8). Empagliflozin group received a standard diet enriched by 0.01% empagliflozin for 6 weeks. Data are expressed as mean ± SEM; *** p ˂ 0.001.