Table 2.

Biochemical parameters in hHTG rats treated with empagliflozin compared to control.

Parameter	Units	Control	Empagliflozin
SOD	U/mg	0.139 ± 0.008	0.126 ± 0.006
GSH-Px	µM NADPH/min/mg	322 ± 21	380 ± 17 *
GR	nM NADPH/min/mg	87 ± 4	101 ± 3 **
CAT	µM H2O2/min/mg	1556 ± 194	2074 ± 110 *
CD	nM/mg	36.9 ± 1.6	41.1 ± 3.3
TBARS	nM/mg	1.91 ± 0.12	1.50 ± 0.11 *

Data are expressed as mean ± SEM; * p ˂ 0.05, ** p ˂ 0.01. SOD: superoxide dismutase; GSH-Px: glutathione peroxidase; GR: glutathione reductase; CAT: catalase; CD: conjugated dienes; TBARS: thiobarbituric acid reactive substances. Control group (n = 7) and empagliflozin group (n = 8). Empagliflozin group received standard diet enriched by 0.01% empagliflozin for 6 weeks.