Table 5.

Parameters of oxidative stress in kidney cortex.

Parameter	Units	Control	Empagliflozin
SOD	U/mg	0.067 ± 0.01	0.088 ± 0.01 *
GSH-Px	µM NADPH/min/mg	128 ± 12	186 ± 15 **
GR	nM NADPH/min/mg	54.4 ± 3.2	57.3 ± 3.7
CAT	µM H2O2/min/mg	17.7 ± 1.42	20.1 ± 1.09
CD	nM/mg	24.3 ± 1.34	22.3 ± 1.93
TBARS	nM/mg	0.681 ± 0.02	0.560 ± 0.03 **

Data are expressed as mean ± SEM; * p < 0.05, ** p < 0.01. Statistical significance was determined by the unpaired Student t-test. SOD: superoxide dismutase; GSH-Px: glutathione peroxidase; GR: glutathione reductase; CAT: catalase; CD: conjugated dienes; TBARS: thiobarbituric acid reactive substances. Control group (n = 7) and empagliflozin group (n = 8). Empagliflozin group received standard diet enriched by 0.01% empagliflozin for 6 weeks.