Figure 5.

Effect of xyloglucan on eosinophil infiltration in the BALF of OVA-sensitized mice. AR-mice exposed a meaningful proliferation of eosinophil cells in the nasal mucosa, compared to the sham group. Treatment with XG significantly reduced eosinophil cell count comparable to single treatments with antihistamine and mast cell stabilizer. In addition, co-administration of XG based spray and antihistamine as well as corticosteroid treatment similarly reduced eosinophil infiltration. Data are representative of at least three independent experiments. Values are means ± SEM. One-Way ANOVA test. *** p < 0.001 vs. Sham; ° p < 0.05 vs. AR + vehicle; °° p < 0.01 vs. AR + vehicle; °°° p < 0.001 vs. AR + vehicle; +++ p 0.001 vs. AR + Corticosteroid. ns: not significant.