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. 2021 Sep 28;22(19):10472. doi: 10.3390/ijms221910472

Figure 7.

Figure 7

Effect of XG treatment on histological evaluation of nasal mucosa. OVA-challenged nasal mucosa showed edema and tissue inflammation (G, histological score N) compared to the sham groups (A–F, histological score N). XG-based spray treatment significantly reduced tissue injury (H,I, histological score N); the reduction in OVA-tissue damage was also considerable in single treatments with mast cell stabilizer (J, histological score N) and antihistamine (K, histological score N). XG and antihistamine co-administration showed a meaningful protection in histological injury (L, histological score N) like corticosteroid group (M, histological score N). Data are representative of at least three independent experiments. Values are means ± SEM. One-Way ANOVA test. *** p < 0.001 vs. Sham; °° p < 0.01 vs. AR + vehicle; °°° p < 0.001 vs. AR + vehicle; +++ p 0.001 vs. AR + Corticosteroid.