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. 2021 Sep 28;22(19):10472. doi: 10.3390/ijms221910472

Figure 12.

Figure 12

Effect of XG treatment on MUC5AB and MUC5AC expressions. MUC5AB and MUC5AC expression were increased in AR-mice compared to the sham group (A,B). XG single treatments considerably reduced the mRNA expression for both mucins with similar efficacy to the to the antihistamine and mast-cell stabilizer treatments (A,B). Moreover, XG and antihistamine co-treatment has been shown to decrease MUC5AB and MUC5AC expression, analogously to treatment with corticosteroid (A,B). Data are representative of at least three independent experiments. Values are means ± SEM. One-Way ANOVA test. *** p < 0.001 vs. Sham; ° p < 0.05 vs. AR + vehicle; °° p < 0.01 vs. AR + vehicle; °°° p < 0.001 vs. AR+vehicle; +++ p 0.001 vs. AR+Corticosteroid. ns: not significant.