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. 2021 Sep 30;22(19):10628. doi: 10.3390/ijms221910628

Table 2.

Matrix of the central composite rotational design (CCRD) (coded and real variables).

Treatments Independent Variable Dependent Variable
Agar-Agar (g) Chitosan (g) Glycerol (%m Glycerol/m Dry Polymer Mass) TS (MPa) EB (%)
1 −1 (0.20) −1 (0.40) −1 (18.09) 3.03 ± 0.74 41.10 ± 2.62
2 +1 (0.80) −1 (0.40) −1 (18.09) 10.36 ± 0.94 25.60 ± 2.29
3 −1 (0.20) +1 (0.60) −1 (18.09) 11.15 ± 2.96 30.76 ± 2.82
4 +1 (0.80) +1 (0.60) −1 (18.09) 6.79 ± 2.86 24.46 ± 3.48
5 −1 (0.20) −1 (0.40) +1 (41.09) 1.31 ± 0.19 17.99 ± 0.32
6 +1 (0.80) −1 (0.40) +1 (41.09) 5.63 ± 1.56 17.45 ± 2.65
7 −1 (0.20) +1 (0.60) +1 (41.09) 4.39 ± 1.02 34.07 ± 3.90
8 +1 (0.80) +1 (0.60) +1 (41.09) 7.09 ± 1.03 25.23 ± 3.20
9 −1.68 (0.00) 0 (1.00) 0 (30.00) 3.11 ± 0.18 51.04 ± 3.64
10 +1.68 (1.00) 0 (1.00) 0 (30.00) 9.47 ± 2.53 14.90 ± 2.20
11 0 (0.50) −1.68 (0.00) 0 (30.00) 4.13 ± 0.71 26.30 ± 3.78
12 0 (0.50) +1.68 (2.00) 0 (30.00) 4.57 ± 1.56 17.88 ± 2.77
13 0 (0.50) 0 (1.00) −1.68 (10.00) 10.59 ± 1.84 23.37 ± 3.10
14 0 (0.50) 0 (1.00) +1.68 (50.00) 3.54 ± 0.69 18.18 ± 3.91
15 0 (0.50) 0 (1.00) 0 (30.00) 8.88 ± 1.04 22.95 ± 1.83
16 0 (0.50) 0 (1.00) 0 (30.00) 8.08 ± 2.09 22.16 ± 3.21
17 0 (0.50) 0 (1.00) 0 (30.00) 10.467 ± 0.28 21.00 ± 1.68

TS: tensile strength at break; EB: elongation at break.