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. 2021 Sep 28;22(19):10440. doi: 10.3390/ijms221910440

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Functional scheme summarizing the predicted dopamine/trace amines metabolic pathways taking place in human enterocytes of the small intestine. This scheme is based on the mining of human expression atlases and on previously published biochemical and/or functional data obtained in intestinal or non-intestinal cells. The molecules included in this scheme comprise: angiotensin-converting enzyme 2 (ACE2), solute carrier family 6 member 19 (SLC6A19), solute carrier family 3 member 1 (SLC3A1), solute carrier family 7 member 9 (SLC7A9), dopa-decarboxylase (DDC), sulfotransferase family 1A member 1 (SULT1A1), sulfotransferase family 1A member 2 (SULT1A2), sulfotransferase family 1A member 3 (SULT1A3), cytochrome P450 family 2 subfamily D member 6 (CYP2D6), monoamine oxidase A (MAOA), monoamine oxidase B (MAOB), solute carrier family 3 member 2 (SLC3A2), solute carrier family 7 member 8 (SLC7A8) and solute carrier family 6 member 10 (SLC16A10).