Table 2.

Mining of single cell RNA-seq data obtained from the analysis of human gut cells.

Cell Type and Intestinal Segment	Genes of Interest with Reported Presence in the Molecular Signatures
Enterocytes
ileum	ACE2, SLC6A19, SLC7A9, SLC3A1, DDC, MAOA, MAOB, CYP2D6, SULT1A1, SULT1A2, SULT1A3
colon rectum	none none
Enteroendocrine cells ileum colon rectum	ACE2, SLC6A19, SLC7A9, SLC3A1, MAOA, SULT1A2 none none
Paneth cells
ileum	SLC6A19, SLC7A9, SLC3A1, DDC, MAOA, CYP2D6, SULT1A1, SULT1A2
colon rectum	none none
Goblet cells ileum colon rectum	SLC7A9, DDC, MAOA, SULT1A1, SULT1A2 none none
Stem cells ileum colon rectum	DDC, MAOA, SLC3A1, none none
Transit amplifying cells illeum colon rectum	DDC, MAOA none none

Gene symbols: angiotensin-converting enzyme 2 (ACE2), solute carrier family 6 member 19 (SLC6A19), solute carrier family 7 member 9 (SLC7A9), solute carrier family 3 member 1 (SLC3A1), dopa-decarboxylase (DDC), monoamine oxidase A (MAOA), monoamine oxidase B (MAOB), cytochrome P450 family 2 subfamily D member 6 (CYP2D6), sulfotransferase family 1A member 1 (SULT1A1), sulfotransferase family 1A member 2 (SULT1A2), sulfotransferase family 1A member 3 (SULT1A3).