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. 2021 Sep 22;22(19):10210. doi: 10.3390/ijms221910210

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scheme 2 — Conjugation of 7α-acetoxy-6β-hydroxyroyleanone with self-assembly inducers: a = squalene-type chain using a labile linker, DMAP, EDC·HCL, dry CH₂Cl₂; b = oleic acid, DMAP, DCC, dry CH₂Cl₂; c = 1-bromododecane, NaH, dry THF. The reaction conditions are reported in the experimental section.