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. 2021 Sep 22;22(19):10210. doi: 10.3390/ijms221910210

Scheme 3.

Scheme 3

Conjugation of 7α-acetoxy-6β-12benzyloxyroyleanone with self-assembly inducers: a = oleic acid, DMAP, DCC, dry CH2Cl2; b = squalene-type chain using a labile linker, DMAP, EDC·HCL, dry CH2Cl2. The reaction conditions are reported in the experimental section.