Table 4.
Multiple linear regression analysis of uremic toxins independently associated with circulating levels of miR-126.
| miR-126 | β | p-Value |
|---|---|---|
| eGFR (CKD-Epi) (per 1 mL/min/1.73 m²) | 0.13 | 0.03 |
| Platelet count (per 1/mm3) | 0.15 | 0.001 |
| Hemoglobin (per 1 g/dL) | 0.13 | 0.003 |
| Age (per year) | −0.13 | 0.01 |
| Sdc-1 (mg/dL) | −0.12 | 0.01 |
| Total IS (mg/dL) | 0.07 | 0.37 |
| Free IS | −0.26 | 0.03 |
| Total pCS (mg/dL) | −0.06 | 0.35 |
| Free pCS | 0.04 | 0.64 |
| Total pCG (mg/dL) | −0.54 | 0.02 |
| Free pCG | 0.58 | 0.11 |
| Total IAA (mg/dL) | −0.10 | 0.34 |
| Free IAA | 0.13 | 0.24 |
Abbreviations: IS, indoxyl sulfate; pCS, para-cresyl-sulfate; pCG, p-cresylglucuronide; and IAA, indole acetic acid. Significant correlations are marked in bold.