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. 2021 Sep 28;22(19):10461. doi: 10.3390/ijms221910461

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Metal-based magnetic composites as functional hard template in fabricating typical materials. (A,B) Structural information of pure phased Fe₃O₄ and biocompatibility were tested in normal and cancer cell lines. Effect of Fe₃O₄ on the viability of cancer cells and two types of normal cells; (C) FE-SEM image structural information of Fe₃O₄@C core-shell particles; (D,E) The proposed mechanism of ROS generation by MnWO_X-PEG under ultrasound irradiation. Microscopy images of H&E and TUNEL-stained tumor slices; (F) Illustration of the fabrication of FeWOx–PEG–RGD NPs for (T₂/T₁-weighted) MR/CT dual-modal imaging-guided PTT/PDT/CDT synergistic therapy. These are reprinted with permission from Ahamed et al. (A,B: 2013, Elsevier), Bakhshi et al. (C: 2020, Elsevier), Gong et al. (D,E: 2019, Wiley) and Cheng et al. (F: 2021, RSC).