UGCG-guide-119 forward:	5′-caccgcgattacacctcaacaaga-3′;
UGCG-guide-119 reverse:	5′-aaactcttgttgaggtgtaatcgc-3′.
UGCG-guide-451 forward:	5′-caccgccatgtcagtaagcgtatc-3′;
UGCG-guide-451 reverse:	5′-aaacgatacgcttactgacatggc-3′.