Skip to main content
. 2021 Sep 23;22(19):10255. doi: 10.3390/ijms221910255

Figure 2.

Figure 2

Interruption in DFMO-induced cell death by polyamines in SKOV-3 cells. (A) SKOV-3 cells were incubated with polyamines for 1–5 days. Cell growth rate and proliferation were determined using the PrestoBlue and CellTiter-Glo assays, respectively. (B) Polyamines were treated with a concentration of 0 or 50 μM for 48 h in DFMO-treated SKOV-3 cells, and the cell viability in DFMO/polyamines-treated SKOV-3 cells was measured using the PrestoBlue assay. (C) ODC-1 activity in DFMO/polyamines-treated SKOV-3 cells was detected using the Luciferase Assay (Luciferase Assay System). The controls were treated with 0.1% DMSO. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with the controls.