Table 2.
KEGG pathways identified in top 50 upregulated and top 50 down regulated differentially expressed genes in tumor macrophages derived from KO compared with controls using RNA-seq.
| KEGG ID | Term Description | False Discovery Rate |
|---|---|---|
| mmu00340 | Histidine metabolism | 0.0066 |
| mmu04115 | p53 signaling pathway | 0.0066 |
| mmu04610 | Complement and coagulation cascades | 0.0066 |
| mmu05202 | Transcriptional misregulation in cancer | 0.0066 |
| mmu05215 | Prostate cancer | 0.0066 |
| mmu04350 | TGF-beta signaling pathway | 0.0091 |
| mmu01522 | Endocrine resistance | 0.0104 |
| mmu05322 | Systemic lupus erythematosus | 0.0104 |
| mmu04066 | HIF-1 signaling pathway | 0.0122 |
| mmu05205 | Proteoglycans in cancer | 0.0187 |
| mmu04068 | FoxO signaling pathway | 0.0244 |