Figure 6.

CTX-serum increased the binding of cancer cells to ECM in vitro. Plates coated with matrigel were pre-treated with PBS-serum or CTX-serum in the presence of MMPi or vehicle (Veh) before incubation with tGFP-MVT1 cells to assay their ability to allow cancer cell adhesion. Top: Quantification of cells per well after the indicated treatments (n = 20 from 4 independent experiments). Bottom: Representative images. Scale bar, 100 μm. Bars indicate mean ± SEM; two-way ANOVA with post hoc Holm–Šídák correction; ** p < 0.01.