Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 23;22(19):10253. doi: 10.3390/ijms221910253

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The metabolic pathways and related functions of pyrimidine nucleotides. (A): CAD participates in de novo pyrimidine nucleotides synthesis and metabolic pathways in mammalian cells. (B): CAD plays a role in the synthesis of nucleic acid precursors, activation intermediates and membrane. UMP, uridine monophosphate. UDP, uridine diphosphate. UTP, uridine triphosphate. CTPS, cytidine triphosphate synthetase. CTP, cytidine triphosphate. UR, uridine. dUDP, deoxy-uridine diphosphate. dUTP, deoxy-uridine triphosphate. dUMP, deoxy-uridine monophosphate. dTTP, deoxy-thymidine triphosphate. CDP, cytidine diphosphate. dCDP, deoxy-cytidine diphosphate. dCTP, deoxy-cytidine triphosphate. TS, thymidylate synthase. CDP-choline, cytidine diphosphate-choline. UDP-Glu, uridine diphosphate-glucose. RRM2, ribonucleotide reductase M2.