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. 2021 Sep 29;22(19):10551. doi: 10.3390/ijms221910551

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Deconvoluted mass spectra of HSA (5 × 10⁻⁷ M) in 2 mM ammonium acetate solution at pH 6.8 incubated at 37 °C for 48 h with (b) Pt2c, [Pt((1-hexyl-1H-imidazol-2yl)(methanamine)(1-hexyl-1H-imidazole)]²⁺, (c) Pt-VIII, [Pt((R)-8-amino-5,6,7,8-tetrahydroquinoline)(1-hexyl-1H-imidazole)]²⁺ and (d) Pt-IV, [Pt((R)-8-aminoquinoline)(1-hexyl-1H-imidazole)]²⁺ in 1:3 protein-to-platinum compound molar ratio.

(a) Deconvoluted mass spectra of HSA (5 × 10⁻⁷ M) in 2 mM ammonium acetate solution at pH 6.8 incubated at 37 °C for 48 h with (b) Pt2c, [Pt((1-hexyl-1H-imidazol-2yl)(methanamine)(1-hexyl-1H-imidazole)]²⁺, (c) Pt-VIII, [Pt((R)-8-amino-5,6,7,8-tetrahydroquinoline)(1-hexyl-1H-imidazole)]²⁺ and (d) Pt-IV, [Pt((R)-8-aminoquinoline)(1-hexyl-1H-imidazole)]²⁺ in 1:3 protein-to-platinum compound molar ratio.