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. 2021 Sep 30;22(19):10642. doi: 10.3390/ijms221910642

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effects of morroniside administration on an OVX-induced osteoporosis mouse model. Mice received different concentrations of morroniside (2 and 10 mg/kg/day) for 12 weeks. (A) Bone mineral density of right femur was determined using PIXI-mus bone densitometer during the experiment. (B) Representative images of right femur were obtained using Micro-CT analysis. Sham; sham-operated, OVX; ovariectomized mice, MO; morroniside treatment. ^* p < 0.05 vs. OVX (one-way ANOVA with Tukey’s honest significant difference post hoc test).