ChiCTR1800018769.

Study name	The application of patient reported outcomes in preventing relapse of depression
Methods	Randomised parallel trial, China
Participants	Inclusion criteria: patients aged 18 to 65 years, diagnosed with current major depressive disorder, who have been treated for 6‐12 weeks in acute phase Exclusion criteria: presence of other mental health conditions, suicidal ideation, pregnancy
Interventions	Quote: "The patients in PRO treatment group were required to complete the self‐evaluation of PHQ‐9, GAD‐7, AIS, MARS, Q‐LES‐Q‐SF and other related symptoms, medication compliance and quality of life according to the regulations. The patients in PRO treatment group were asked to complete the self‐evaluation periodically based on the way of Wechat public signal platform, and then the doctors made a comprehensive evaluation according to the results of self‐evaluation and adjusted the treatment according to the research plan. At the same time, the patients were given health education. The self‐evaluation, feedback and patient education were all pushed on the platform of Wecaht public number. Finally, the differences between the two groups were compared."
Outcomes	Main outcome: sustained response time (measured with Hamilton Rating Scale for Depression) Other outcomes: relapse rate, compliance
Starting date	April 2018
Contact information	Hu Chang‐Qing (coannhu@126.com)
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