ChiCTR1900020846.

Study name	A study for perioperative symptom management in patients with lung cancer based on patient‐reported outcomes
Methods	Randomised parallel trial, China
Participants	Inclusion criteria: people aged 18 to 75 years, diagnosed with primary lung cancer (clinical stage I‐IIIA), waiting to receive surgery and willing to answer a repeated electronic questionnaire on a smartphone or tablet. Exclusion criteria: neoadjuvant therapy, other malignant tumours, inability to understand the study requirements.
Interventions	Quote: "After enrolment, all the patients will use their WeChat app to connect with the participating specialists’ WeChat app via a mini programme (ePRO Cell). Then, they will be taught how to use the programme. The ePRO questionnaires will be set to send to the patients’ WeChat app automatically after randomisation. Patients are required to complete the ePRO questionnaires on their smartphones or tablets before surgery (baseline, typically 1–3 days before the operation), daily after surgery (in‐hospital, typically 1 to 7 days after the operation) and twice a week after discharge until 4 weeks or the start of postoperative oncological treatment (typically collecting PRO data six to eight times after discharge). In a hospital setting, if the patients do not complete the ePRO questionnaires within the scheduled time, an electronic reminder (e‐reminder) and up to two bedside reminders will be delivered at the same day. After discharge, if the patients fail to complete the ePRO questionnaires within the scheduled time, an e‐reminder and up to two phone reminders will be delivered with 24 hours." (Protocol)
Outcomes	Main outcome: mean symptom threshold events using the MDASI lung cancer‐specific scale Other outcomes: symptom severity, daily functioning and quality of life, revisit rate after discharge
Starting date	1 December 2018 (estimated completion date 31 December 2020)
Contact information	Qiang Li (liqiang@sichuancancer.org)
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