Skip to main content
. 2021 Oct 1;22(19):10678. doi: 10.3390/ijms221910678

Figure 1.

Figure 1

PPAR-α mRNA expression in the hippocampus of socially isolated (SI) mice and its correlation with aggressive behavior. (A) A group of mice that failed to develop aggressive behavior (here termed SI non-aggressive, SI-NAG) during protracted social isolation was separated from the SI mice that showed high aggressive behavior scores (SI-AGG). Decreased PPAR-α mRNA expression in the hippocampus of SI-AGG mice was observed when compared with GH or SI-NAG mice (one-way ANOVA: * p = 0.03; F = 3.8). Values are means ± S.E.M. of eight control (GH), eight SI-AGG, and seven SI-NAG mice. (B) A significant negative correlation exists between PPAR-α mRNA expression and aggressive behavior (Pearson’s r = −0.67; * p = 0.03, n = 8).