APC |
antigen presenting cells |
CIN |
cervical intraepithelial neoplasia |
CPS |
combined positive score |
CRISPR |
clustered regularly interspaced palindromic repeats |
CTLA-4 |
cytotoxic T lymphocyte associated protein 4 |
HPV |
human papilloma virus |
ICI |
immune checkpoint inhibitors |
IHC |
immunohistochemistry |
LAG-3 |
lymphocyte-activation gene 3 |
mDOR |
median duration of response |
MHC |
major histocompatibility complex |
NECC |
neuroendocrine carcinoma of the cervix |
NSCLC |
non-small cell lung carcinoma |
ORR |
objective response rate |
OS |
overall survival |
PD-1 |
programmed death-1 |
PDL1 |
programmed death ligand-1 |
SCC |
squamous cell carcinoma |
TALENs |
Transcription Activator-Like Effector Nucleases |
TIGIT |
T cell immunoglobulin and ITIM domain |
TILs |
tumour infiltrating lymphocytes |
TIM-3 |
T cell immunoglobulin and mucin-domain–containing molecule 3 |
TMB |
tumour mutational burden |
VEGF |
vascular endothelial growth factor |