. 2021 Oct 6;22(19):10803. doi: 10.3390/ijms221910803

Table 3.

Aptamers targeting thrombin whose complexes have been structurally characterized.

Name	DNA or RNA	Sequence (5′ → 3′)	Reference
TBA	DNA	GGTTGGTGTGGTTGG	[80]
mTBA	DNA	3′-GGT-5′-5′-TGGTGTGGTTGG-3′	[81]
TBAΔT3	DNA	GGN^ΔTGGTGTGGTTGG	[82]
TBAΔT12	DNA	GGTTGGTGTGGN^ΔTGG	[82]
TBA-T4W	DNA	GGTT^WGGTGTGGTTGG	[83]
TBA-T4K	DNA	GGTT^KGGTGTGGTTGG	[83]
TBA-3L	DNA	GGT^LTGGTGTGGTTGG	[84]
TBA-3G	DNA	GGT^GTGGTGTGGTTGG	[84]
TBA-3Leu	DNA	GGT^LeuTGGTGTGGTTGG	[84]
RE31	DNA	GTGACGTAGGTTGGTGTGGTTGGGGCGTCAC	[85]
NU172	DNA	CGCCTAGGTTGGGTAGGGTGGTGGCG	[86]
Toggle-25t	RNA	GGGAAC^FAAAGC^FU^FGAAGU^FAC^FU^FU^FAC^FC^FC^F	[87]
Toggle-25t/AF113-18	RNA	GGGAAC^FAAAGC^FU^SeGAAGU^FS2ACU^FU^SeAC^FC^FC^F	[88]
HD22_27mer	DNA	GTCCGTGGTAGGGCAGGTTGGGGTGAC	[89]

N^Δ represents abasic nucleotides; T^W and T^K represent C5-modified nucleotides; T^L, T^G and T^Leu represent N3-modified nucleotides; C^F and U^F represent 2′-fluoropyrimidine nucleotides; U^Se represents 2′-methylselenyluridine nucleotides; and ^S2 represents phosphorodithioate linkage.