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. 2021 Oct 7;22(19):10848. doi: 10.3390/ijms221910848

Figure 1.

Figure 1

Behavioural effects of the coadministration of effective dose of ESC (10 mg/kg) and GAL(1-15) (1 nmol) in the forced swimming test (FST). Saline or ESC was administered intraperitoneal (ip) 23, 5, and 1 h before the test. aCSF, GAL(1-15) or M871 were injected intracerebroventricular (icv) 15 min before the test. Data represent mean ± SEM of immobility and swimming time in FST during the 5 min test period (n = 7–11 rats per group). In (A) * p < 0.05 versus OBX SS+aCSF and OBX ESC10mg+aCSF, in (B) *** p < 0.001 versus OBX SS+aCSF, according to one way ANOVA followed by Fisher multiple comparison test.