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. 2021 Oct 7;22(19):10848. doi: 10.3390/ijms221910848

Figure 3.

Figure 3

Behavioural effects of knockdown 5HT1A model of the coadministration of effective dose of ESC (10 mg/kg) and GAL(1-15) (1 nmol) in the forced swimming test (FST). Saline or ESC was administered intraperitoneal (ip) 23, 5, and 1 h before the test. aCSF or GAL(1-15) was injected intracerebroventricular (icv) 15 min before the test. Data represent mean ± SEM of immobility (A) and swimming (B) time in FST during the 5 min test period (n = 8–13 rats per group). There are no significant differences according to one way ANOVA followed by Fisher multiple comparison test.