Figure 12.

Effects of compounds 1, 2, and 3 on the rats’ immobility time in the FST. Compounds 1, 2 and 3 were administered i.p. 60 min, before the test. The rats were observed for 5 min. The data are presented as the mean ± SEM of 6–8 rats. Geometrical figures represent obtained raw data; the symbol shapes for all raw data were standarized for all doses and compounds. The data were statistically evaluated by one-way ANOVA followed by Bonferroni’s post-hoc test, * p < 0.05, ** p < 0.01, *** p < 0.001 vs. respective vehicle-treated group, (one-way ANOVA for immobility time for FST: F(3,26) = 10.6150; p < 0.001 (for compound 1), F(3,26) = 5.8561, p < 0.01 (for compound 2) and F(3,26) = 6.8104, p < 0.01 (for compound 3)). Details shown in Supplementary Table S5.