Table 1.
Cpd | Ki (nM) ± SD | ||||
---|---|---|---|---|---|
a 5-HT6 | a D2 | 5-HT1A | a 5-HT2A | a 5-HT7 | |
1
2 3 |
6 ± 1 6 ± 2 21 ± 5 |
320 ± 19 421 ± 29 1506 ± 338 |
4760 ± 1191 521 ± 73 3643 ± 816 |
484 ± 77 209 ± 19 5047 ± 752 |
5706 ± 967 5202 ± 1247 19,940 ± 2357 |
Ref b | 7 ± 1 | 9 ± 2 | - | - | - |
SD—standard deviation; a receptors affinity that was revealed previously [21]; b olanzapine.