Figure 4.

Volcano plot showing the log₂ fold change values of 715 proteins plotted against their associated −log₁₀ p-values. Dots representing individual proteins were divided in four different groups: p-value > 0.05 (black); p-value < 0.05 (grey); p-value < 0.05, 1.5-fold higher abundance in colon (orange); p-value < 0.05, 1.5-fold higher abundance in spleen (blue). For both sample groups two proteins, being typical higher abundant in colon or spleen tissue, respectively are highlighted and named (see Supplementary Table S4).