Skip to main content
. 2021 Oct 1;22(19):10686. doi: 10.3390/ijms221910686

Table 1.

Reaction of 2H-cyclohepta[b]furan-2-ones with active methylenes.

graphic file with name ijms-22-10686-i001.jpg
Entry R R’ R’’ Product, Yield [%]
1 CO2Me H H 35a, 91
2 CO2Me i-Pr H 35b, 93
3 SO2Me H H 35c, 87
4 SO2Me i-Pr H 35d, 89
5 S+Me2 H H 35e, 90
6 SMe H H No reaction
7 I i-Pr H No reaction
8 graphic file with name ijms-22-10686-i002.jpg i-Pr H 35f, 88
9 graphic file with name ijms-22-10686-i003.jpg i-Pr H 35g, 90
10 graphic file with name ijms-22-10686-i004.jpg i-Pr H 35h, 88
11 graphic file with name ijms-22-10686-i005.jpg i-Pr H 35i, 92
12 CO2Et H OMe 35j, 85