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. 2021 Oct 4;10(19):4584. doi: 10.3390/jcm10194584

Table 3.

Plasma concentrations of selected proinflammatory factors in patients with MM.

Untreated Group without PN
(n = 59)
Treated Group with PN (n = 34) Treated Group without PN (n = 27) p-Value *
Treated Group with PN vs.
Untreated Group without PN
p-Value *
Treated Group without PN vs.
Untreated Group without PN
p-Value *
Treated Group with PN vs.
Treated Group without PN
Mean ± SD Mean ± SD Mean ± SD
TNF-α (pg/mL) 4.44 ± 2.71 3.84 ± 2.05 3.55 ± 2.32 0.3222 0.0428 0.2327
IL-6 (pg/mL) 4.48 ± 8.32 3.04 ± 2.73 2.77 ± 2.25 0.9300 0.9221 0.9593
Chitinase3 (pg/mL) 59,018 ± 39,791.33 50,706 ± 33,595.14 40,502 ± 27,212.7 0.4437 0.0346 0.2013
IL-10 (pg/mL) 3.44 ± 7.00 2.07 ± 0.83 1.64 ± 0.34 0.9554 0.005 0.0017
CCL2 (pg/mL) 190.94 ± 81.88 299.24 ± 165.30 252.41 ± 91.15 0.0018 0.002 0.4458
IL-1β (pg/mL) 1.28 ± 0.48 1.93 ± 0.35 1.70 ± 0.48 <0.0001 <0.0001 0.0023
IFN-γ (pg/mL) 2.79 ± 1.50 14.40 ± 8.03 11.76 ± 3.19 <0.0001 <0.0001 0.2659

* Mann–Whitney test. In bold, p-values < 0.05.