Table 2.
The concentrations of tested proteins in the study groups.
| Tested Variables in CSF |
Median (Range of Interquartile) | p (U-Mann–Whitney) | |
|---|---|---|---|
| AD | CTRL | ||
| Aβ42/40 ratio | 0.032 (0.03–0.04) | 0.066 (0.06–0.08) | <0.001 |
| Aβ42 | 513 (460–655) | 926 (815–1004) | <0.001 |
| Tau (pg/mL) | 676 (591–1058) | 222 (191–273) | <0.001 |
| pTau181 (pg/mL) | 86.7 (73.2–122) | 37.5 (34–42.9) | <0.001 |
| Ng (ng/mL) | 920 (737–1202) | 487 (435–580) | <0.001 |
| NPTXR (pg/mL) | 13.2 (10.8–16.3) | 19 (16.9–21.6) | <0.001 |
| NPTXR/Ng ratio | 0.014 (0.009–0.019) | 0.395(0.039–0.044) | <0.001 |
Note: Ng—neurogranin, NPTXR—neuronal pentraxin receptor, Aβ42—amyloid Beta 1-42, Aβ42/40—amyloid Beta 1-42 to 1-40 ratio, AD—Alzheimer’s disease, CTRL—control, CSF—Cerebrospinal fluid.