Table 4.
Sensitivity and specificity of ADI-R Deaf adaptation and ADOS-ASD thresholds by the NICE guideline standard clinical assessment for the comparator assessment.
| No of True Positives | No of False Negatives | No of True Negatives | No of False Positives | Sensitivity (95% CI) |
Specificity (95% CI) |
|
|---|---|---|---|---|---|---|
| ADI-R Deaf adaptation (narrow threshold) |
51 | 7 | 48 | 10 | 88% (77%, 95%) | 83% (71%, 91%) |
| ADOS-2 Deaf adaptation (narrow threshold) |
38 | 20 | 47 | 11 | 66% (52%, 78%) | 81% (69%, 90%) |
| ADOS-2 Deaf adaptation (wider threshold) |
43 | 15 | 42 | 16 | 74% (61%, 85%) | 72% (59%, 83%) |
| ADI-R Deaf adaptation and ADOS-2 Deaf adaptation (narrow threshold) |
35 | 23 | 55 | 3 | 60% (47%, 73%) | 95% (86%, 99%) |
| ADI-R Deaf adaptation and ADOS 2 Deaf adaptation (wider threshold) |
39 | 19 | 53 | 5 | 67% (81%, 97%) | 91% (81%, 97%) |
| ADI-R Deaf adaptation or ADOS-2 Deaf adaptation (narrow threshold) |
54 | 4 | 40 | 18 | 93% (83%, 98%) | 69% (55%. 80%) |
| ADI-R Deaf adaptation or ADOS-2 Deaf adaptation (wider threshold) | 55 | 3 | 37 | 21 | 95% (86%, 99%) | 64% (50%, 76%) |
NB; ‘or’ refers to thresholds being met for one or the other instrument; ‘and’ refers to thresholds being met for both instruments.