Table 4.
Accuracy of ROTEM parameters and platelet count for the association with clinically evident VTE
| Parametera | Area under the curve (95% CI) | Optimal cutoff | Sensitivity (%) | Specificity (%) |
| Preoperative EXTEM A10 | 0.75 (0.61-0.88) | ≥ 57 | 73 | 80 |
| Preoperative EXTEM MCF | 0.84 (0.75-0.92) | ≥ 69 | 81 | 79 |
| Preoperative EXTEM CFT | 0.88 (0.81-0.96) | ≤ 81 | 90 | 76 |
| Preoperative INTEM A10 | 0.68 (0.56-0.79) | ≥ 60 | 91 | 53 |
| Preoperative INTEM MCF | 0.79 (0.71-0.87) | ≥ 67 | 90 | 62 |
| Preoperative INTEM CFT | 0.89 (0.81-0.97) | ≤ 65 | 81 | 86 |
| Postoperative INTEM A10 | 0.81 (0.71-0.90) | ≥ 64 | 91 | 65 |
| Postoperative INTEM MCF | 0.85 (0.80-0.90) | ≥ 75 | 100 | 75 |
| Postoperative INTEM CFT | 0.80 (0.69-0.91) | ≤ 56 | 78 | 73 |
The area under the curve and optimal cutoff (Youden index) values with corresponding sensitivity and specificity are presented; A10 = clot amplitude at 10 minutes; MCF = maximum clot firmness; CFT = clot formation time.
a
Preoperative INTEM clot formation time, preoperative EXTEM clot formation time, and postoperative INTEM maximum clot firmness demonstrated the highest levels of accuracy.