Table 6.
In vitro growth inhibitory activity of OE and F1–F4 tested against four human cancer cell lines: SW620, CFPAC-1, MCF-7 and HepG2 and non-transformed fibroblast cell line (HFF-1).
| Sample | IC50 (µg/mL) | ||||
|---|---|---|---|---|---|
| SW620 | CFPAC-1 | MCF-7 | HepG2 | HFF-1 | |
| OE | 13.14 ± 5.02 | 22.69 ± 4.14 | 36.20 ± 3.87 | 30.11 ± 1.44 | 6.48 ± 0.12 |
| F1 | 158.78 ± 86.47 | 73.03 ± 14.63 | 67.01 ± 5.42 | 231.18 ± 46.13 | 207.80 ± 21.60 |
| F2 | 0.82 ± 0.14 | 5.61 ± 2.11 | 5.21 ± 1.03 | 2.58 ± 0.57 | 0.39 ± 0.03 |
| F3 | 5.73 ± 2.97 | 7.93 ± 0.12 | 14.63 ± 9.41 | 6.48 ± 1.91 | 6.95 ± 1.96 |
| F4 | 18.76 ± 2.61 | 48.80 ± 1.12 | 42.76 ± 5.96 | 37.66 ± 3.47 | 9.97 ± 1.55 |
| 5-FU | 0.83 ± 0.03 | 0.84 ± 0.09 | 0.01 ± 0.001 | 7.18 ± 1.95 | 0.12 ± 0.02 * |
* Results obtained on lung fibroblast WI38. Values are expressed as mean value ± standard deviation of triplicate measurement.