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DBGWAS analysis of ENRO resistance in 95 Belgian M. bovis isolates and M. bovis PG45. Significant associations between the ENRO non-WT phenotype (n = 8) and genotype could be found for two known fluoroquinolone gene targets, i.e., the gyrA (A) and parC (B) genes. Further in-depth analysis identified two and four nonsynonymous mutations in the GyrA and ParC protein, respectively. Amino acid positions are labeled according to classic Escherichia coli numbering.
