Figure 18.
Antibody array analysis of proapoptopic protein synthesis in U87 (A,E), U118 (B,F), U251 (C,G) and T98 (D,H) glioma cells treated with complexes of graphene oxide functionalised with antisense miRNA-21 (A–D) and miRNA-21 by electroporation (E–H). GO + antisense miRNA-21 treatment results in the upregulation synthesis of Bcl-2-associated X protein (BAX), caspase-8, heat shock protein 27 (HSP27), heat shock protein 60 (HSP60), TNF-related apoptosis-inducing ligand (TRAILR-2), second mitochondria-derived activator of caspase (Smac) and cytochrome c in U118 (B) and U251 (C).