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The calculated pharmacokinetic parameters of rats in different groups after administration of a single oral dose of berberine of 50 mg/kg body weight.
| Brb Solution | Brb Liposomes | Brb Hyaluronate Based Liposomes | |
|---|---|---|---|
| Cmax (ng/mL) | 21.51 ± 4.71 | 36.54 ± 0.77 | 67.79 ± 1.12 |
| Tmax (h) | 1 | 8 | 8 |
| AUC | 194.8 ± 6.73 | 439.9 ± 14.39 | 854 ± 23.69 |
| Relative bioavailability | - | 2.26 | 4.38 |
Data represents mean ± standard deviation.
