Table 1.
Overview of the included publications on signal transduction: (a) PI3K/Akt/mTOR; (b) AMPK; (c) ERK; (d) P38, JNK and MAPK signal transduction pathways.
(a) | mTOR Ser2448 | Akt Ser473 | Akt Thr308 | Akt Total |
---|---|---|---|---|
Repressed | [11,44,142] | [11,101,103,142,144,149,150,151,152,153] | [154] | [152,155] |
Activated | [38] | |||
Unchanged/ambiguous | [145] | [145] | ||
(b) | AMPKα Thr172 | AMPKβ Ser108 | ||
Repressed | ||||
Activated | [113,142,145,146,152,164,166,167] | [152] | ||
Unchanged/ambiguous | ||||
(c) | ERK Thr202/Tyr204 | |||
Repressed | [55,103,143,151,174,177,178] | |||
Activated | [11] | |||
Unchanged/ambiguous | [176] | |||
(d) | P38 Thr180/Tyr182 | JNK Thr183/Tyr185 | ||
Repressed | [101,103,112,174] | [35,103,177] | ||
Activated | [11,175,176,177] | [11,176] | ||
Unchanged/ambiguous | [178] |