Table 1.
Demographics, baseline characteristics, laboratory values of ESRD and non-ESRD patients admitted to the ICU with sepsis.
| Variable | Non-ESRD | ESRD | p-value |
|---|---|---|---|
| N = 8073 | N = 730 | ||
| Female gender, N (%) | 3603 (44.63) | 349 (47.81) | .098 |
| Age (year), mean ± SD | 61.53 ± 19.86 | 65.50 ± 15.04 | <.0001 |
| Admission diagnosis, N (%) | |||
| Non-operative | 7557 (93.61) | 707 (96.85) | .0005 |
| Post-operative | 516 (6.39) | 23 (3.15) | |
| Chronic diseases, N (%) | |||
| Cardiac disease | 2096 (26.02) | 236 (32.42) | .0002 |
| Respiratory disease | 2211 (27.46) | 169 (23.21) | .0137 |
| Liver disease | 536 (6.66) | 81 (11.11) | <.0001 |
| Immunosuppression | 1016 (12.62) | 37 (5.08) | <.0001 |
| Tracheostomy, N (%) | 807 (10.0) | 78 (10.68) | .5535 |
| Vasopressor, N (%) | 3429 (42.47) | 426 (58.36) | <.0001 |
| Diabetes Mellitus, N (%) | 3788 (46.92) | 460 (63.01) | <.0001 |
| Mechanical ventilation, N (%) | 4869 (60.31) | 469 (64.25) | .0372 |
| APACHE II, mean ± SD | 22.99 ± 8.11 | 28.69 ± 7.78 | <.0001 |
| Bilirubin, µmol/l, mean ± SD | 36.83 ± 80.68 | 39.55 ± 88.50 | .4688 |
| GCS, mean ± SD | 11.46 ± 3.96 | 10.91 ± 4.04 | .0004 |
| Creatinine, µmol/l, mean ± SD | 140.4 ± 126.5 | 415.1 ± 217.4 | <.0001 |
| Lactic Acid, mg/dl, mean ± SD | 3.10 ± 3.43 | 3.53 ± 3.95 | .0076 |
| INR, mean ± SD | 1.56 ± 1.05 | 1.69 ± 1.07 | .0022 |
| PaO2/FiO2, mean ± SD | 204.6 ± 117.6 | 219.4 ± 129.1 | .0033 |
APACHE II: Acute Physiology and Chronic Health Evaluation II; GCS: Glasgow Coma Scale; INR: International normalised ratio; PaO2/FiO2: the ratio of partial pressure of oxygen to the fraction of inspired oxygen.