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. 2021 Oct 13;2(12):e704–e714. doi: 10.1016/S2666-5247(21)00214-7

Table 2.

LAMP, dPCR, and qPCR overall sensitivities and specificities

LAMP dPCR qPCR
Sensitivity
Reitsma 83·3% (76·9–88·2) 94·1% (88·9–96·9) 92·7% (88·3–95·6)
Latent 86·2% (20·7–99·9) 95·8% (54·9–100·0) 93·4% (60·9–99·9)
Specificity
Reitsma 96·3% (93·8–97·8) 78·5% (57·4–90·8) 92·9% (87·2–96·2)
Latent 94·3% (49·1–100·0) 73·8% (0·9–100·0) 93·1% (47·1–100·0)

Data are % (95% CI). Sensitivities and specificities for each molecular test were estimated using Reitsma's bivariate random-effects model (Reitsma) and Bayesian latent class bivariate model (latent). LAMP=loop-mediated isothermal amplification. dPCR=digital PCR. qPCR=quantitative PCR.