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. 2021 Oct 6;48(6):210. doi: 10.3892/ijmm.2021.5043

Figure 1.

Figure 1

mRNA expression of SETD7 decreases during chondrogenic differentiation. (A) Alcian blue staining of differentiated ATDC5 cells cultured in micromass at 1 and 20% O2. Scale bar, 100 µm. mRNA expression of (B) aggrecan, (C) SOX9, (D) COL2A1 and (E) SETD7 during chondrogenic differentiation at 1% O2. Results are representative of ≥3 independent experiments. *P<0.05, ***P<0.001 vs. 0 days. SETD7, SET domain containing 7; HIF-1α, hypoxia inducible factor-1α; COL2A1, collagen II, α1; SOX9, SRY-related box gene 9.