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. 2021 Oct 4;48(6):208. doi: 10.3892/ijmm.2021.5041

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Copyright: © Sun et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Exosomal si-LOC100129516 suppresses atherosclerotic progression in vivo via upregulation of the PPARγ/LXRα/ABCA1 signaling pathway. (A-D) Western blot assays were performed to detect the expression levels of PPARγ, LXRα and ABCA1 in the aortic tissues of ApoE^−/− mice. n=6. ^**P<0.01 vs. control group; ^##P<0.01 vs. AS group. siRNA, small interfering RNA; PPARγ, peroxisome proliferator-activated receptor γ; LXRα, liver X receptor α; ABCA1, phospholipid-transporting ATPase ABCA1; ctrl, control; AS, atherosclerosis; Exo, exosome.