Table 4.

Overview of studies, registries, and surveys studying the influence of adherence on clinical outcomes

QUALIFY [36]a	BIOSTAT-HF [21]b	Norwegian Heart Failure Registry [37]a	Austrian HF registry [23]a
All-cause mortality (HR 0.45)	All-cause mortality (HR 0.57) for ACEi/ARB	All-cause mortality (HR 0.65)	All-cause mortality (HR 0.55)
CV mortality (HR 0.44)	All-cause mortality (HR 0.41) for BB
HF mortality (HR 0.44)

^aPoor adherence: defined as use of < 50% of target doses; good adherence: defined as use of ≥ 50% of target dosage

^bPoor adherence: defined as use of < 50% of target doses; good adherence: defined as use of 100% of target dosage