Table 2.
Study, outcomes, and total number of patients/patients receiving bromocriptine
| Study | Total number of patients/patients receiving bromocriptine | Type of study | Outcomes |
| Sliwa et al. [46] | 20/10 | Prospective single-center, randomized | Patients treated with bromocriptine had greater improvement in LVEF at 6 months than the control group, and fewer experienced the composite endpoint compared with the control group (death, NYHA class III/IV, or LVEF < 35% at 6 months) |
| Yameogo et al. [47] | 96/48 | Prospective single-center, randomized | LVEF was similar at entry but higher in the bromocriptine group at 2 weeks and at 3, 6, and 12 months. Mortality at 6 months was higher in both groups but lower in the bromocriptine-treated women |
| Hilfiker-Kleiner et al. [48] | 2 different regiments of bromocriptine (1 week in 27 patients vs. 8 weeks in 31 patients) | Randomized trial | The investigators postulated an association between bromocriptine and the favorable outcomes. The study was limited by the lack of a control group not receiving bromocriptine |
| Haghikia et al. [27] | 115/64 | Observational | Bromocriptine in addition to standard therapy was associated with higher rate of improvement in LVEF, but there was no significant difference in overall rates of recovery |
| REBIRTH (Randomized Evaluation of Bromo-criptine in Myocardial Recovery Therapy) | 200 | A randomized double-blind, placebo control study | Under evaluation |