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. 2021 Sep 17;199(5):507–515. doi: 10.1007/s00408-021-00475-1

Table 1.

Diagnostic tests performed for the study of patients with chronic cough: Scores for frequency of indication

Median (IQR) Percentage with the highest score (8–10), n (%)
Family physicians#
(n = 620)
Pulmonologists
(n = 92)
Allergists
(n = 62)
Family physicians#
(n = 620)
Pulmonologists
(n = 92)
Allergists
(n = 62)
p-value*
Chest x-ray 9 (7–10) 10 (10–10) 8 (5–10) 432 (69.7) 88 (95.7) 31 (50.0)  < 0.001
Simple spirometry 6 (3–8) 10 (9–10) 10 (10–10) 234 (37.7) 75 (81.5) 55 (88.7)  < 0.001
Bronchodilator test 8 (5–9) 10 (10–10) 10 (9–10) 311 (50.2) 87 (94.6) 52 (83.9)  < 0.001
Methacholine test 1 (1–1) 5 (3–7) 5 (2–7) 7 (1.1) 13 (14.1) 15 (24.2)  < 0.001
FeNO test 1 (1–1) 7 (3–10) 8 (3–10) 7 (1.1) 43 (46.7) 35 (56.5)  < 0.001
Capsaicin test 1 (1–1) 1 (1–1) 1 (1–1) 5 (0.8) 1 (1.1) 1 (1.6) 0.799
Complete blood count 8 (5–9) 8 (5–10) 8 (5–10) 310 (50.0) 48 (52.2) 31 (50.0) 0.926
Total IgE 6 (3–8) 5 (3–7) 9 (6–10) 198 (31.9) 45 (48.9) 36 (58.1)  < 0.001
Specific IgE 4 (1–7) 5 (4–7) 8 (5–10) 113 (18.2) 21 (22.8) 31 (50.0)  < 0.001
Chlamydia/Mycoplasma serology 1 (1–3) 2 (1–3) 2 (1–5) 24 (3.9) 2 (2.2) 5 (8.1) 0.175
Esophageal pH monitoring 1 (1–1) 3 (2–5) 3 (1–5) 17 (2.7) 5 (5.4) 6 (9.7) 0.012

Physicians scored the frequency with which they indicate each test on a scale ranging from 1 = “Never” to 10 = “Always”; IQR, interquartile range; FeNO, fractional exhaled nitric oxide

*p-values refer to the differences in the percentages with the highest score (8–10) across specialties

#Although there might be variations from center to center, in general primary care physicians have no access or limited access to the following diagnostic tests: methacholine test, FeNO test, capsaicin test, specific Ig E, and esophageal pH monitoring. These tests are performed by pulmonologists and allergists (methacholine test, FeNO test, capsaicin test) or by gastroenterologists (esophageal pH monitoring)