Table 1.
Demographic information, clinical background, brain-related data and estimated microglial density per mm3 in individuals with schizophrenia (Schiz), bipolar disorder (BD) and non-psychiatric controls
| Variable | Schiz (n = 17) | BD (n = 13) | Controls (n = 17) | F value | p value |
|---|---|---|---|---|---|
| Age at death (yrs) | 45.3 ± 6.7 | 46.0 ± 7.9 | 45.4 ± 5.7 | 0.127 | 0.88 |
| Gender ratio (F:M) | 06:11 | 09:04 | 04:13 | 0.044 | 0.84 |
| Age at onset (yrs) | 21.6 ± 6.5 | 24.1 ± 7.8 | 0.905 | 0.44 | |
| Duration of illness (yrs) | 22.9 ± 11.2 | 21.9 ± 4.8 | 0.28 | 0.598 | |
| Brain weight (g) | 1405 ± 111 | 1399 ± 135 | 1473 ± 154 | 4.493 | 0.013 |
| Brain pH | 6.49 ± 0.242 | 6.52 ± 0.295 | 6.69 ± 0.243 | 2.958 | 0.062 |
| Post-mortem interval (h) | 30.4 ± 11.9 | 35.2 ± 13.6 | 29.1 ± 13.8 | 2.550 | 0.082 |
| Microglia/mm3 | 5529 ± 1100 | 5956 ± 927 | 6020 ± 1229 | 2.585 | 0.079 |
F, female; g, grams; h, hours; M, male; yrs, years