Dependence of the gating current fluctuations on the height of the energy barriers, the friction coefficient, and the applied voltage. (A) (b) and (c) show the plots of variance versus mean current produced by altering the total energy profiles as shown in (a) (black line is the original energy profile of the full model, green and blue lines are the altered energy profiles). An increase in the barrier height results in a decrease in the apparent charge. (B) Variance-mean current plots obtained with the full model with the original setting (black data points) and with the intercharge distance increased or decreased by 1 Å (orange and blue, respectively). Insets show the corresponding gating charge distributions. To see this figure in color, go online.